Fish Model - CEMC - Trent University

This model predicts fish concentrations for neutral organic chemicals through dietary and respiratory uptake including loss by respiration, egestion, metabolic biotransformation, and growth dilution. Equations used in all calculations and references for equations and default values are included in the spreadsheet and inputs are highlighted in blue for ease of use. Results can be found at the bottom of the worksheet including fish concentration and fugacity, bioconcentration factor (BCF), biomagnification factor (BMF), and bioaccumulation factor (BAF).

Features of the Fish model:

Estimates fish concentrations due to uptake by respiration and diet due to presence of a chemical in water
Provides a small fish database
Default species and values are provided based on a Lake Ontario Foodweb
Treats any neutral organic chemical
Accounts for uptake and loss due to respiration, diet, metabolic biotransformation, and growth dilution
Spreadsheets can be edited
Includes instructions sheet, guidance for choosing input values, and more in-depth information available in the publications

Based on the following publications:

Clark, K.E., Gobas, F.A.P.C., Mackay, D. 1990. Model of chemical uptake and clearance by fish from food and water. Environmental Science and Technology. 24: 1203-1213.
Gobas, F.A.P.C, McCorquodale, J.R., Haffner, G.D. 1993. “Intestinal absorption and biomagnification of organochlorines”. Environ. Toxicol. Chem. 12: 567-576.
Mackay, D. 2002. "Multimedia Environmental Models: The Fugacity Approach - Second Edition", Lewis Publishers, Boca Raton, pp. 213-220
Webster, E., Cowan-Ellsberry, C.E., McCarty, L. 2004. Putting science into PBT evaluations. Environ. Toxicol. Chem. 23: 2473-2482. (for the concise definitions of BCF, BAF, and BMF)

Required Input Data:

Chemical Properties

Molar mass
Henry’s law constant
Log K_OW
Metabolic half-life

Environmental Properties

Data collection temperature
Water concentration
Organic Carbon (OC) density
OC water concentration
Species Properties
Lipid content
Mass
Diet concentration
Diet lipid content
Diet mass

Model output includes:

Water, and organism fugacities
Z-values and D-values
Fish rate constants
Fish concentration, quantity
BCF
BAF
BMF
Chemical residence time in fish
Model checks using mass balance and concentration/fugacity calculations

Please read the software license before downloading the software. Use of the software constitutes your agreement to abide by the terms and conditions set out in the license agreement. Please report any problems to Prof. Mark Parnis.

Download Fish Model (Excel Spreadsheet Version 4.04 August 18, 2023)

Download Fish Model (Visual Basic Version 2.00)

VB program coded by Angela McLeod, Jennifer Hubbarde, and Eva Webster